One of the other big factors, and this is something where only you can have this conversation with yourself to figure out, is what type of employer/employer style are you/are you going to have?
This has alot to do with your personality trait, and will greatly influence how, one day as a practice owner, you'll run things. Basically put, are you a hands on everything micro-manager, or a big picture, its fine as long as it gets done macro-manager???
The micro-manger will be going over every last detail, even if you implicitly trust your office manager/front desk coordinator. You'll be the type that typically will have individual employee reviews quarterly, and tends to have a higher staff turnover rate as a result of your staff sooner or later feeling irritated by you watching their every move. Often your staff will quit before you might have to fire them with this managerial style.
The macro-manager will look more big picture, and as such, issue a task or goal for the office, such as say "I'd like to see a 5% decrease in accounts receivable this year" and not worry too much about how your employees accomplish this. You'll trust that your employees have enough smarts/ability to accomplish this. You'll tend to have far more infrequent employee reviews, and are a hands off boss. You'll tend in this situation to have to fire an employee rather than them quitting.
Each style has thier own place, and neither is right or wrong, its just what works best for your and your employees, and often the final product is a combo of the two.
As for the true business nuances, alot of that is what you'll end up hiring people for. Tax issues, with how complicated and how fluid the tax laws are, your best bet is to hire an accountant you trust to guide you through this area, a good accountant 99% of the time will save you way more in taxes each year than you'll pay them!
