Does decrease in compliance increase or decrease diastolic pressure?

[beatsbydre]

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I am getting conflicting info from different usmle sources. I think it makes more sense for diastolic pressure to rise when there is a decrease in compliance since there is less space for the blood to travel through.

However, this thread states the opposite (http://forums.studentdoctor.net/showthread.php?t=795676).

Thanks!!

 

[Phloston]

I am getting conflicting info from different usmle sources. I think it makes more sense for diastolic pressure to rise when there is a decrease in compliance since there is less space for the blood to travel through.

However, this thread states the opposite (http://forums.studentdoctor.net/showthread.php?t=795676).

Thanks!!

I have not clicked on the link above, but increased diastolic pressure occurs with decreased compliance and increased elasticity. Compliance is your ability to expand. Elasticity is your ability to recoil. I've even seen PubMed articles (when I was doing my PhD lit review) where researchers mix that up.

This is why hypercalcaemia can induce diastolic hypertension. Unlike skeletal muscle, which relies on Ca2+ directly from the sarcoplasmic reticulum, smooth and cardiac muscle can take up Ca2+ directly from the extracellular space. In the case of diastolic hypertension, increased Ca2+ leads to increased calmodulin- and MLCK-induced tonicity and decreased expansion per change in pressure.

 

[Phloston]

Btw: I just read the first response to the link you've shared above and the person writes "the arteries expand (increase in diameter) due to elasticity..." I just stopped reading the thread because the posters have confused their terminology.

 

[beatsbydre]

Awesome. Thanks!