Dosage conversion

[DrZion]

I need a website or chart that shows how to convert IV doses (D/t) to PO doses(D/t) & vice versa.

Also the equivalent doses of drugs in same class. e.g Ramipril 40mg = lisinopril ?mg

 

[aboveliquidice]

I need a website or chart that shows how to convert IV doses (D/t) to PO doses(D/t) & vice versa.

Also the equivalent doses of drugs in same class. e.g Ramipril 40mg = lisinopril ?mg

LexiComp - Micromedex - Drug Facts & Comparisons...

 

[DrZion]

LexiComp - Micromedex - Drug Facts & Comparisons...

Does Lexi-Comp tell you that a particular oral dose is equivalent to some IV dose?

I'm looking for a reference or website that tells you the exact doses and how to choose equivalent drug in the same drug class (ACE-I, HMGCoA-I, CCB & so on)

 

[aboveliquidice]

Does Lexi-Comp tell you that a particular oral dose is equivalent to some IV dose?

I'm looking for a reference or website that tells you the exact doses and how to choose equivalent drug in the same drug class (ACE-I, HMGCoA-I, CCB & so on)

Historically - this information is listed in Drug Facts and Comparisons. If you go to charts and special topics in Lexi - which I have on my PDA at any given time - it tells you dosing regimens.

Lisinopril for HTN = 10 to 40mg / day (max 40mg / day) - Qday
Ramipril for HTN = 2.5 to 20 mg/ day = qday to BID

You typically have to look at the BP lowering effect at dose (which is also in the chart)

 

[StaviZFingerZ]

I need a website or chart that shows how to convert IV doses (D/t) to PO doses(D/t) & vice versa.

Also the equivalent doses of drugs in same class. e.g Ramipril 40mg = lisinopril ?mg

You're looking for an IV to PO coversion and automatic therapeutic substitution list. This is much more involved than a simple list.

In order to implement this at a hospital, you'll need more than a list. You'll need to provide comparative efficacy studies for each drug you're wanting to convert. IV to PO is little easier since bioavailability is what you're looking for. But IV to PO requires a patient clinical status requirement before you can simply convert.

 

[aboveliquidice]

You're looking for an IV to PO coversion and automatic therapeutic substitution list. This is much more involved than a simple list.

In order to implement this at a hospital, you'll need more than a list. You'll need to provide comparative efficacy studies for each drug you're wanting to convert. IV to PO is little easier since bioavailability is what you're looking for. But IV to PO requires a patient clinical status requirement before you can simply convert.

I haven't the slightest idea what he is referring to... You should probably go with the wisdom of a soon-to-be P3 on this one. That guy - I heard he is the "washing lettuce guy" at McDowell's...

Ten years from now - he still won't be on Fries!!!

 

[DrZion]

I haven't the slightest idea what he is referring to... You should probably go with the wisdom of a soon-to-be P3 on this one. That guy - I heard he is the "washing lettuce guy" at McDowell's...

Ten years from now - he still won't be on Fries!!!

lol