doubts in patho-micro

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anjoliey

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hi
can some one please help me with the following questions....
1.Which of the following represents the primary function of S-IgA
A.Aggregates micro-organisms and prevents colonization
B.Activates complement in secretory fluids
C.Promotes phagocytosis by monocytes
D.Activates mast cells
E.Activates NK cells.

2.Which of the following diseases can be classified as an endogenous infection?
A.Syphillis
B.Dysentery
C.Gas ganrene
D.Scarlet fever
E.Sub acute infectious bacterial endocarditis.


thanks in advance
anjoliey
 
1 . A - FACT

2. E - Caused by Strep. viridans, an endogenous organism.

Hope this helps




anjoliey said:
hi
can some one please help me with the following questions....
1.Which of the following represents the primary function of S-IgA
A.Aggregates micro-organisms and prevents colonization
B.Activates complement in secretory fluids
C.Promotes phagocytosis by monocytes
D.Activates mast cells
E.Activates NK cells.

2.Which of the following diseases can be classified as an endogenous infection?
A.Syphillis
B.Dysentery
C.Gas ganrene
D.Scarlet fever
E.Sub acute infectious bacterial endocarditis.


thanks in advance
anjoliey
 
TALAL said:
1 . A - FACT

2. E - Caused by Strep. viridans, an endogenous organism.

Hope this helps

why not clostridium which causes gas gangrene , it is endogenous as well ?
so...?
 
Clostridium is not an endogenous organism. Yes it causes gas gangrene, but the question is about an organism NORMALLY part of the human flora. That is what I presume endogenous refers too.

Hope it helps



mekha said:
why not clostridium which causes gas gangrene , it is endogenous as well ?
so...?
 
TALAL said:
Clostridium is not an endogenous organism. Yes it causes gas gangrene, but the question is about an organism NORMALLY part of the human flora. That is what I presume endogenous refers too.

Hope it helps

clostridium is a part of the normal flora , clostridium perfringens and difficile found in gut ,is normal flora, Most (95 - 99.9%) of these are anaerobes, represented by Bacteroides, Bifidobacterium, anaerobic streptococci and Clostridium. These organisms inhibit the growth of other pathogens but some can be opportunistic (e.g. C. difficile can produce pseudomembranous colitis).
 
Hmm. this is getting interesting. Well so is Strep viridans which causes SBE. More than two third of cases of gas gangrene are caused by innoculation of wounds by spores and by surgical procedures. But you are right that one third are endogenous.

I guess the point is that SBE is always caused by Strep from the gingiva.

Anyway am enjoying this duel with you. mekha 🙂





mekha said:
clostridium is a part of the normal flora , clostridium perfringens and difficile found in gut ,is normal flora
 
hi
answers r:-
1.A
2.C
HOPE THIS HELPS
!
anjoliey said:
hi
can some one please help me with the following questions....
1.Which of the following represents the primary function of S-IgA
A.Aggregates micro-organisms and prevents colonization
B.Activates complement in secretory fluids
C.Promotes phagocytosis by monocytes
D.Activates mast cells
E.Activates NK cells.

2.Which of the following diseases can be classified as an endogenous infection?
A.Syphillis
B.Dysentery
C.Gas ganrene
D.Scarlet fever
E.Sub acute infectious bacterial endocarditis.


thanks in advance
anjoliey
 
TALAL said:
Hmm. this is getting interesting. Well so is Strep viridans which causes SBE. More than two third of cases of gas gangrene are caused by innoculation of wounds by spores and by surgical procedures. But you are right that one third are endogenous.

I guess the point is that SBE is always caused by Strep from the gingiva.

Anyway am enjoying this duel with you. mekha 🙂

i like it too 👍
its good we discuss which helps us both(mutualism)..hehe

# Examples of human normal flora

1. Actinomyces spp.
2. aerobic micrococci
3. Bacteroides
4. spp. Bifidobacterium
5. spp. Candida
6. spp. Clostridium
7. spp. Citrobacter
8. spp. Corynebacterium
9. spp. Corynebacterium
10. xerosis diptheroids
11. Enterobacter
12. spp. Enterococcus
13. spp. Escherichia coli
14. Fusobacterium
15. spp. Hemophilus
16. spp. Klebsiella
17. spp. Lactobacillus
18. spp. Neisseria
19. spp. Pityrosporum
20. spp. Propionibacterium
21. acnes Proteus
22. spp. Pseudomonas
23. spp. Shigella
24. spp. Staphylococcus
25. spp. Staphylococcus aureus
26. Staphylococcus epidermidis
27. Streptococcus
28. spp. Streptococcus pneumoniae
29. Treponema
30. spp. Trichomonas vaginalis
 
No, now I'm pretty sure it is SBE. It's just that the entire purpose of sterilization is to get rid of spores by Bacillus and Clostridium. Think like this. If it were a endogenous infection why sterilize?






mekha said:
i like it too 👍
its good we discuss which helps us both(mutualism)..hehe

# Examples of human normal flora

1. Actinomyces spp.
2. aerobic micrococci
3. Bacteroides
4. spp. Bifidobacterium
5. spp. Candida
6. spp. Clostridium
7. spp. Citrobacter
8. spp. Corynebacterium
9. spp. Corynebacterium
10. xerosis diptheroids
11. Enterobacter
12. spp. Enterococcus
13. spp. Escherichia coli
14. Fusobacterium
15. spp. Hemophilus
16. spp. Klebsiella
17. spp. Lactobacillus
18. spp. Neisseria
19. spp. Pityrosporum
20. spp. Propionibacterium
21. acnes Proteus
22. spp. Pseudomonas
23. spp. Shigella
24. spp. Staphylococcus
25. spp. Staphylococcus aureus
26. Staphylococcus epidermidis
27. Streptococcus
28. spp. Streptococcus pneumoniae
29. Treponema
30. spp. Trichomonas vaginalis
 
TALAL said:
No, now I'm pretty sure it is SBE. It's just that the entire purpose of sterilization is to get rid of spores by Bacillus and Clostridium. Think like this. If it were a endogenous infection why sterilize?


ruling out sabe
1 it needs forced inoculation or and it can be nasocomial which can cause sabe
2 in extensive antibiotic use normal flora is supervened by c.difficile causing
pseudomemebranous colitis .

howz that
 
😉 Let's turn this into a Mekha vs Talal thread or maybe an India vs Pakistan (if you are from India that is) 😉

Okay as far as C. difficile is concerned yes that is endogenous but the question is about gas gagrene. Secondly, what would be your answer considering that the VAST MAJORITY of cases of gas gangrene are caused by wound infection. Okay now I am definitely convinced it is SBE.

Waiting for your answer 😀



mekha said:
ruling out sabe
1 it needs forced inoculation or and it can be nasocomial which can cause sabe
2 in extensive antibiotic use normal flora is supervened by c.difficile causing
pseudomemebranous colitis .

howz that
 
TALAL said:
😉 Let's turn this into a Mekha vs Talal thread or maybe an India vs Pakistan (if you are from India that is) 😉

Okay as far as C. difficile is concerned yes that is endogenous but the question is about gas gagrene. Secondly, what would be your answer considering that the VAST MAJORITY of cases of gas gangrene are caused by wound infection. Okay now I am definitely convinced it is SBE.

Waiting for your answer 😀

hey i like ur reply ,
sabe is caused by nasocomial inf too,enterococci is responsible for nasocomial infection of sabe .
clostridium prefringens which causes myonecrosis (g.gangrene ).muscle necrosis which happens inside caused by antibiotic supervention dominating the normal flora and and allowing c perfringens to cause this , so why not endogenous too (intestine)

i am havin a good time here ,,u have a pretty cool challenging personality friend . 👍
 
Okay now you are getting way toooooooooo detailed 😳 Do you have a micro book by your side? I think let's call it a truce till someone else joins in. My final thoughts - Gas gangrene is endogenous in a very small number of cases (googled that right now). Those cases are those of immunocompromised patients. SBE is only endogenous. Besides, remember the antibiotic prophylaxis given to patients with valvular heart disease. The antibiotic targets endogenous organisms, right?

Haha.. I think I might have won this argument 😉



mekha said:
hey i like ur reply ,
sabe is caused by nasocomial inf too,enterococci is responsible for nasocomial infection of sabe .
clostridium prefringens which causes myonecrosis (g.gangrene ) is endogenous too (intestine)

i am havin a good time here ,enjoyin too ,u have a good challenging personality friend . 👍
 
TALAL said:
Okay now you are getting way toooooooooo detailed 😳 Do you have a micro book by your side? I think let's call it a truce till someone else joins in. My final thoughts - Gas gangrene is endogenous in a very small number of cases (googled that right now). Those cases are those of immunocompromised patients. SBE is only endogenous. Besides, remember the antibiotic prophylaxix given to patients with valvular heart disease. The antibiotic targets endogenous organisms, right?

Haha.. I think I might have won this argument 😉

muscle necrosis which happens inside caused by antibiotic supervention dominating the normal flora and allowing c perfringens to cause this , so why not endogenous ? (intestine)

hey ur arguments r cool ,but cant accept .......lol
 
That is colitis you are talking about not gas gagrene. Besides antibiotic overuse is associated with colitis not gas gangrene. I think your arguments are starting to weaken 😉



mekha said:
muscle necrosis which happens inside caused by antibiotic supervention dominating the normal flora and allowing c perfringens to cause this , so why not endogenous ? (intestine)

hey ur arguments r cool ,but cant accept .......lol
 
TALAL said:
That is colitis you are talking about not gas gagrene. Besides antibiotic overuse is associated with colitis not gas gangrene. I think your arguments are starting to weaken 😉

i think u r getting weak here ,guess who is right with clostridium perfringens dominating

http://jcp.bmjjournals.com/cgi/content/full/54/10/748
 
Barely awake I skimmed through that article. The article deals with diarrhoea by Clostridium P, not gas gangrene. The question also deals with gas gangrene. My point is that it may cause diarrhoea but not gas gagrene.

Think of it like this. We are both right. Since the curve in Patho is so good, one questio would not make much of a difference.

Oh and by the way, the answer is SBE 😉 .

And now I' going to sleep 😴


mekha said:
i think u r getting weak here ,guess who is right with clostridium perfringens dominating

http://jcp.bmjjournals.com/cgi/content/full/54/10/748
 
Barely awake I skimmed through that article. The article deals with diarrhoea by Clostridium P, not gas gangrene. The question also deals with gas gangrene. My point is that it may cause diarrhoea but not gas gagrene.

Think of it like this. We are both right. Since the curve in Patho is so good, one question would not make much of a difference.

Oh and by the way, the answer is SBE 😉 .

And now I' going to sleep 😴


mekha said:
i think u r getting weak here ,guess who is right with clostridium perfringens dominating

http://jcp.bmjjournals.com/cgi/content/full/54/10/748
 
TALAL said:
That is colitis you are talking about not gas gagrene. Besides antibiotic overuse is associated with colitis not gas gangrene. I think your arguments are starting to weaken 😉


gas gangrene is caused byc perfringens which is a normal flora ,.
spores ---c tetani or welchi comes .
Nonenterococcal group D organisms is not endogenous ,ok , I am winning,


* The condition is subacute ,WON
 
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