EK Bio 30-min Exam Lecture 1

[capnamerica]

Question 3.) Why is B wrong? The passage states that enzymes and chaperons are involved in determining the shape...

Question 20.) The logic of why the answer is C. ADP still doesn't sit well with me. If ADP is an allosteric activator of PFK, then why does the reaction PFK catalyze produce even more ADP? This seems like +ve FB, which wouldn't make sense!

Also, are hydrogen bonds not considered to be covalent bonds?

Thanks SDN!

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[startswithb]

For #3, chaperones and enzymes help assist with the folding process. They are not involved in determining the shape, like answer choice B states.

As for #20, the PFK catalyzed reaction is the committed step, which is why it's the most important regulatory step. The step does cause ATP-> ADP, but I don't think that matters as much since the overall product of glycolysis is still ATP. So activating the PFK reaction in response to low cellular energy signified by a high ADP concentration still leads to more ATP.