I was told before you matriculate. However, in my case...
I was actually one English class short of the requirements of nearly every school I applied to. And I got multiple acceptances
It was never even mentioned. Some of the (online) applications even had me fill in every prereq, and a little yellow flag came up next to '2nd semester of English.' I still got an interview, and got a good spot on the waitlist. So, if you are a decent applicant, they might not even care.