10+ Year Member
5+ Year Member
- Jul 2, 2008
- Dental Student
is the only difference between these two the location?
location is one part of the difference, however the "promoter region" is where you will get the binding of the RNA polymerase, along with other transcription factors, which forms the initiation complex. The enhancers can be located at great distances from the promoter, sometimes even within the coding sequence (downstream of the promoter) and will typically bind to transcription activators, which will activate/initiate transcription. How is the enhancer sequence brought near the promoter sequence? This is accomplished by the looping of the DNA, so that prior to transcription initiation, you have one large initiation complex.