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Anyone who’s used this protocol, do you feel it’s benefical? I used ketamine, lidocaine and precedex infusions during residency with the various adjuncts and never really appreciated a huge difference. Thoughts?
We have several ERAS pathways at my training institution. Few things i/we have noticed
-there does appear to be some reduction length of stay (especially in discussion with surgeons and looking at available data) in certain service lines but we are still collecting data
-Our surgery colleagues have noticed several of patients receiving goal directed fluid therapy have developed AKI on POD1 and POD2 (even if they were kept at the recommended MAP goal). How significant this is we don't know although AKI is an independent predictor of mortality in several disease states. However, maybe this is better than a prolonged ileus due to over-rescuscitation?
-The ketamine drip if left on too long (close to emergence) can lead to some big time PACU delirium or failure to follow commands which prolongs PACU recovery time.
-Our surgery colleagues have noticed several of patients receiving goal directed fluid therapy have developed AKI on POD1 and POD2 (even if they were kept at the recommended MAP goal). How significant this is we don't know although AKI is an independent predictor of mortality in several disease states. However, maybe this is better than a prolonged ileus due to over-rescuscitation?
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It appears there are many ERAS protocols during anesthesia that seem to vary institution to institution, with no real standards. Outcome studies from ERAS anesthesia protocols indeed often show little difference between non-ERAS from measurable anesthesia outcomes but discharge early seems to be the most consistent. Several studies have shown no significant improvement in post operative pain or opioid use in-hospital. Most disturbing is some ERAS publications never outline what their protocol actually is anywhere in the publication.
Restrictive versus Liberal Fluid Therapy for Major Abdominal Surgery NEJM
Published yesterday: ERAS goal-directed/restrictive fluids found to be non-superior to liberal application of fluids... and associated with high instances of AKI.
Anyone who’s used this protocol, do you feel it’s benefical? I used ketamine, lidocaine and precedex infusions during residency with the various adjuncts and never really appreciated a huge difference. Thoughts?
"ERAS" is not a singular protocol and there are substantial differences between institutions, types of surgery, etc. What specific surgery are you talking about?
And yes, for the most part ERAS pathways are beneficial, probably in the same way ARDSnet was helpful in preventing people who trained decades ago from harming their patients with outdated medicine/techniques.
Quit being so vague. 🙂Quit being so clever
We have several ERAS pathways at my training institution. Few things i/we have noticed
-there does appear to be some reduction length of stay (especially in discussion with surgeons and looking at available data) in certain service lines but we are still collecting data
-Our surgery colleagues have noticed several of patients receiving goal directed fluid therapy have developed AKI on POD1 and POD2 (even if they were kept at the recommended MAP goal). How significant this is we don't know although AKI is an independent predictor of mortality in several disease states. However, maybe this is better than a prolonged ileus due to over-rescuscitation?
-The ketamine drip if left on too long (close to emergence) can lead to some big time PACU delirium or failure to follow commands which prolongs PACU recovery time.
I think it's better to stop the ketamine about an hour prior to finishing a case to prevent them from weirding out the pacu nurses.
Goal directed therapy is a sham. We don't have good methods to determine fluid status.
I was more speaking in general. Everyone knows there are variations. Quit being so clever
The way you phrased your initial question made it seem like you didn't know there were variations, since you referred to it as "this protocol." ERAS protocols are very different between specialty and institution, so you have to be more specific...otherwise you're asking people to compare apples and oranges. Not all ERAS protocols, for instance, have ketamine, lidocaine, and Precedex infusions associated with them.
Still being clever
"ERAS" is not a singular protocol and there are substantial differences between institutions, types of surgery, etc. What specific surgery are you talking about?
It seems like you could use a little more cleverness then. 🙂
But for real, all I was asking was whether you wanted information about a specific surgical type.
I don't know what your issue is but apparently I bruised your internet ego with that "inflammatory statement" so you decided to start talking about me instead, when I was providing information for a question that I thought you asked. I guess my presence won't provide anything to this discussion so I'll stop posting on this thread, which is sad because I actually have done plenty of research on ERAS protocols, specifically for colorectal surgery (the surgery specialty with the most data out there for ERAS) and it would have been an interesting discussion.
I'll leave you all with a practice guideline that was published jointly with ASCRS regarding ERAS for colorectal surgery: https://www.fascrs.org/sites/defaul...actice_guidelines_for_enhanced_recovery.3.pdf
I do appreciate the edit to the original post though.
Still being clever
Hey, don't come in here with a question and try to talk down to the people helping you.
I have used the lidocaine and ketamine. I don't believe that they cause harm and maybe help, although not immediately evident. I know there are only a few that show problems with ketamine, but they are in the vast minority. I think most things that limit opioids intraoperatively are going to be beneficial, especially in lower doses. I am excited to try precedex again, but it has been about a decade since I have used it and we still don't have it where I work. Haldol seems to be doing a good job limiting PONV/PDNV that is readily apparent.Anyone who’s used “these protocols”, do you feel theyre benefical? I used ketamine, lidocaine and precedex infusions during residency with the various adjuncts and never really appreciated a huge difference. Thoughts?
I have used the lidocaine and ketamine. I don't believe that they cause harm and maybe help, although not immediately evident. I know there are only a few that show problems with ketamine, but they are in the vast minority. I think most things that limit opioids intraoperatively are going to be beneficial, especially in lower doses. I am excited to try precedex again, but it has been about a decade since I have used it and we still don't have it where I work. Haldol seems to be doing a good job limiting PONV/PDNV that is readily apparent.
Has anyone experienced or read about other recent trends that are promising? What about decadron in blocks? I don't like the variability but have started trying it again.
Clearsite? To determine fluid status for “goal directed therapy”I think it's better to stop the ketamine about an hour prior to finishing a case to prevent them from weirding out the pacu nurses.
Goal directed therapy is a sham. We don't have good methods to determine fluid status.