Evening Primrose Oil + Aspirin Interaction?

[MaRph2009]

Does anyone know how significant is the interaction between Evening Primrose Oil and Aspirin? Clin Pharm did not pop up any interactions.. but Lexi-Comp says there is a major interaction..using the 2 in combination will increase risk of bleeding.

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[Vitamin K]

Does anyone know how significant is the interaction between Evening Primrose Oil and Aspirin? Clin Pharm did not pop up any interactions.. but Lexi-Comp says there is a major interaction..using the 2 in combination will increase risk of bleeding.

It can increase INR (on the warfarin interaction list), but I don't know that I'd consider it a "major" interaction with aspirin...

 

[Rebel78]

If someone was on long-term therapy (daily aspirin or warfarin) I probably wouldn't recommend taking them together. Micromedex lists it as moderate.