UKdent, primary infection and primary lesion are not the same thing. primary infections are subclinical. primary lesions are far worse than secondary lesions (as you described yourself). Prodrome is the tingling/burning/aching that comes before the lesion erupts, which can occur before the primary lesions as well!!! As for the lipid solvent, it means a solvent that dissolved lipid, as in alcohol.
I hate to disagree once again... but you cant have a prodrome before the primary lesions of herpes. Primary lesions occur at the sight of inoculation(in general, by site of inoculation i mean oral cavity or genitals, ect). Prodrome are neurological symptons that occur at the nerve level, which is where herpes lay dormant. Upon a recurrance the virus travels along the nerve with cause the prodrome. Since primary herpes are not reactivated at the nueral ganglia they will not travel along the nerve or cause a prodrome. Prodrome are also often seen in neurological conditions such as migraines and epilepsy. Since these are not due to a specific virus you can have a prodrome before the initial episode, but for our case here with herpes you can not have a prodrome before the first lesion.
A warning sign (prodrome) is experienced by many people in
recurring outbreaks. Warning symptoms which indicate the virus is becoming active, and is on its way to the skin's surface may include:
Warning signs that the virus is active may include:
* itching
* tingling
* numbness
* burning
* general fatigue
* flu-like symptoms
* fever
* swelling of the lymph nodes in the area of outbreak
* headache
* painful urination
* pain in the buttocks, back of legs, lower back
Source :
http://www.herpes-coldsores.com/herpes_symptoms.htm#prodome
One clue to
reactivation for many people is "prodrome," something they feel rather than see. Prodrome can involve an itching or tingling in the genital area, backache, shooting pains through the legs, or other sensations. It often serves as a warning that sores or other skin lesions are soon to come, but not always. In either case, the sensations of prodrome can be taken as a sign that herpes is in its active state.
http://www.herpesdiagnosis.com/herpes.html
Genital herpes is episodic. After the virus enters the body, it multiplies and herpes breaks out. This is the first episode of herpes. After the first episode, the virus becomes dormant and further outbreaks occur when the virus become active again. These are called recurring episodes.
Prodrome occurs before recurring episodes. A day or two before an outbreak occurs; the genital skin gets sensations such as itching, tingling or pain. This period is called prodrome phase. If you keep aware of the prodrome phase and begin medication then itself, you can reduce the intensity of the outbreak substantially.
http://www.doctorgoodskin.com/ds/genitalherpes/prodrome.php
Recurrence Course, Triggers, and Timing
Course of Recurrence. Most cases of herpes simplex recur. The site on the body and the type of virus influence how often it comes back. The virus usually takes the following course:
* Prodrome. The outbreak of infection is often preceded by a prodrome, an early group of symptoms that may include itching skin, pain, or an abnormal tingling sensation at the site of infection. The patient may also have a headache, enlarged lymph glands, and flu-like symptoms. The prodrome, which may be as few as 2 hours or as many as 2 days, steps when the blisters develop. About 25% of the time, recurrence does not go beyond the prodrome stage.
* Outbreak. Recurrent outbreaks of herpes simplex virus (HSV) feature most of the same symptoms at the same sites as the primary attack, but they tend to be milder and briefer. After blisters erupt, they typically heal in 6 - 10 days. Occasionally, the symptoms may not resemble those of the primary episode but appear as fissures and scrapes in the skin or as general inflammation around the affected area.
http://www.umm.edu/patiented/articles/what_symptoms_of_herpes_simplex_virus_000052_2.htm
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