Extended Release to Immediate Release

[pharmleague]

Hey everyone.

Usually when you convert extended release to immediate release, you just take the total daily dose and divide it BID, TID, whatever.

But are there any drugs that you convert differently (besides, say, like Coreg, where the XR has different strengths than the regular)? It seems like there are some, but I can't think of any right now. Thanks.

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[Wheresmyaricept]

Paroxetine and methylphenidate?

 

[zelman]

Usually it'd be IR to ER, not the other way around. Why switch to IR?

 

[xiphoid2010]

Usually it'd be IR to ER, not the other way around. Why switch to IR?

autosub for non-formulary money grabbing patent extension meds.

 

[zelman]

autosub for non-formulary money grabbing patent extension meds.

Certainly a good reason. However, the dose conversion should be in the autosub policy. Is there another reason wherein the answer to this question comes into play?

 

[pharmleague]

My reason for asking is for changing PO meds to be given per feeding tube.

 

[bkiskadd]

Usually it'd be IR to ER, not the other way around. Why switch to IR?

We will do this inpatient, especially for someone in the ICU for things like metoprolol in case the patient becomes hypotensive the effect of the med won't last as long.