Step I FA 2013 error??

[Pinkleton]

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On page 78 of FA 2013 it says that Ehlers Danlos syndrome is most frequently caused by defective type 1 or 5 collagen, whereas in FA 2012 it says type 3 (and the 2012 errata does not correct it). Could this be an error? I thought it was type 3

 

[FIREitUP]

On page 78 of FA 2013 it says that Ehlers Danlos syndrome is most frequently caused by defective type 1 or 5 collagen, whereas in FA 2012 it says type 3 (and the 2012 errata does not correct it). Could this be an error? I thought it was type 3


edit: please delete. someone posted about this already

yeah i noticed that too, googling told me that it's 1 and 3. i don't think there is a type 5 collagen, haha

 

[projectlogic]

yeah i noticed that too, googling told me that it's 1 and 3. i don't think there is a type 5 collagen, haha

It is type 5. It's in the errata for 2012 edition.

 

[FIREitUP]

It is type 5. It's in the errata for 2012 edition.

wikipedia says I and III...and they don't even mention type V in the previous page, that's pretty weird.

 

[projectlogic]

wikipedia says I and III...and they don't even mention type V in the previous page, that's pretty weird.

http://en.wikipedia.org/wiki/Type-V_collagen


The page that you're talking about is talking about the different types of Ehlers-Danlos not different collagen types.

 

[FIREitUP]

http://en.wikipedia.org/wiki/Type-V_collagen


The page that you're talking about is talking about the different types of Ehlers-Danlos not different collagen types.

oh wow that wording could have been better on that wikipedia page. anyways, thanks for the heads up.

 

[werd]

since you asked.... the EDS subtypes are totally crazy. i had to memorize them for my boards, but for step 1 you should probably know type 1 is classic type and is col 5; type 4 is the vascular type and is col 3. Osteogenesis imperfecta and a very rare type of EDS are caused by col 1 mutations.

Ehlers-Danlos syndrome (EDS)
– Type 1 (Gravis): AD, collagen 5.
– Type 2 (Mitis): AD, collagen 5.
– Type 3 (Benign hypermobile): AD, collagen 3.
– Type 4 (Vascular): AD/AR, collagen 3:
– Type 5 (X-linked): X-recessive. Lysyl oxidase deficiency.
– Type 7 (Arthrochalasis multiplex congenita): AD/AR, COL1A/2,
– Type 8 (Periodontitis): Type 3 collagen.
– Type 9 (Occipital horn syndrome): XR Lysyl oxidase.
– Type 10 (Fibronectin): AR, fibronectin.
– Type 11 (Large joint hypermobile): AD: dislocation of large joints
– Progeroid EDS: AR, xylosylprotein 4-beta-galactotransferase.
– EDS with congenital adrenal hyperplasia: AR, tenascin-X