First Aid 2007 Page 318 Error not in May 2007 Update

[DocOfDocs]

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Page 318 in First Aid 2007 has a diagram of the cell cycle and where certain drugs act. "Antimetabolites" has an arrow pointing to the S phase and I'm pretty sure it should be pointing to the G1 phase. Alkylating agents are not mentioned in the diagram and they act in S phase. Am I wrong? Or is the diagram wrong?

Thanks

 

[synapse lapse]

I suck at anti cancer drugs but wiki says S phase: http://en.wikipedia.org/wiki/Antimetabolite I left my kaplan book on those at school so can't look up to confirm what the said.

 

[DocOfDocs]

I am 99% sure there was a diagram in USLME World that had antimetabolites pointing to the G1 phase. One of the two diagrams is wrong, but I tend to believe wiki.

 

[Mediculous]

I am 99% sure there was a diagram in USLME World that had antimetabolites pointing to the G1 phase. One of the two diagrams is wrong, but I tend to believe wiki.

That UW diagram has been brought up before as suspect on this forum. Anti-metabolites alter proper DNA synthesis, which is why I think they effect S phase. Alkylating agents are categorized as cell-cycle non-specific because they exert their effect on formed DNA, which is present in every cycle.