My friend passed this question on to me. Can anyone see this as a valid question for step 1? A 34 year old woman (P:1, G:1) has a 46XY down syndrome child. Genetic analysis revealed she has a t(14q21q) translocation. Assuming her partner is genetically normal, what are the odds that her next child will be phenotypically normal? A) 1/6 B) 1/4 C) 1/3 D) 1/2 E) 2/3 I'm thinking (D) 2/3 with the assumption that monosomy 21 and monosomy 14 will terminate as abortions.