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My friend passed this question on to me. Can anyone see this as a valid question for step 1?
A 34 year old woman (P:1, G:1) has a 46XY down syndrome child. Genetic analysis revealed she has a t(14q21q) translocation. Assuming her partner is genetically normal, what are the odds that her next child will be phenotypically normal?
A) 1/6
B) 1/4
C) 1/3
D) 1/2
E) 2/3
I'm thinking (D) 2/3 with the assumption that monosomy 21 and monosomy 14 will terminate as abortions.
A 34 year old woman (P:1, G:1) has a 46XY down syndrome child. Genetic analysis revealed she has a t(14q21q) translocation. Assuming her partner is genetically normal, what are the odds that her next child will be phenotypically normal?
A) 1/6
B) 1/4
C) 1/3
D) 1/2
E) 2/3
I'm thinking (D) 2/3 with the assumption that monosomy 21 and monosomy 14 will terminate as abortions.