Goldman Hodgkin Kats Equation

[heyyowhatsup333]

Is this equation worth memorizing or just understand how to use it? Has anyone seen it on an MCAT?

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[doctorleospaceman]

I don't think I've seen it at all tbh

 

[Lawpy]

Is this equation worth memorizing or just understand how to use it? Has anyone seen it on an MCAT?

so i looked up what you're talking about and found this

... that looks like a nightmare to deal with

 

[md-2020]

I have no idea what that is, and @Lawper 's elaboration didn't really clear anything up either.

So...either I'm about to be a **** doctor or it's not relevant. Here's hoping!

 

[freak7]

so i looked up what you're talking about and found this

... that looks like a nightmare to deal with

It's just the Nernst equation with a term for each permeate right? It wouldn't be that difficult to memorize aside from remembering that negative ions have flipped orientation.

That being said: No you shouldn't have to memorize it.

 

[Lawpy]

I have no idea what that is, and @Lawper 's elaboration didn't really clear anything up either.

So...either I'm about to be a **** doctor or it's not relevant. Here's hoping!

it looks like a really complicated equation that deals with something about calculating a membrane potential with multiple ions crossing a membrane based on their permeability. i really don't think this equation has any relevance tbh. why would doctors waste their time using a complicated equation like that when simple concepts work better?

It's just the Nernst equation with a term for each permeate right? It wouldn't be that difficult to memorize aside from remembering that negative ions have flipped orientation.

That being said: No you shouldn't have to memorize it.

it's a pain to calculate using that formula. i'm a fan of simple formulas.

 

[JustAPhD]

it looks like a really complicated equation that deals with something about calculating a membrane potential with multiple ions crossing a membrane based on their permeability. i really don't think this equation has any relevance tbh. why would doctors waste their time using a complicated equation like that when simple concepts work better?



it's a pain to calculate using that formula. i'm a fan of simple formulas.

It's actually quite simple, just a little long and intimidating looking. Its bark is worse than its bite. 😉

 

[freak7]

It's actually quite simple, just a little long and intimidating looking. It's bark is worse than its bite. 😉

It's just a generalized Nernst!

 

[Lawpy]

There is also a GHK flux equation

More information here: http://www.math.fsu.edu/~quine/biotopics07/KandSCh3.pdf

To be honest, these equations and concepts look like something found in a graduate level course in biophysics or bioengineering.

It's actually quite simple, just a little long and intimidating looking. It's bark is worse than its bite. 😉

It's just a generalized Nernst!

Not worth it. Waste of time. Just stick with simple equations. I mean doctors even reduced the Henderson-Hasselbalch equation into something like this

 

[redsox93]

we had to use this in my metabolic regulation class. brings back bad memories

 

[freak7]

Not worth it. Waste of time.

I'm not saying it isn't. One definitely shouldn't waste time memorizing that thing. However, it's not as big and scary as the so-called "I hate math" media would have you believe. Fake News.

 

[Lawpy]

I'm not saying it isn't. One definitely shouldn't waste time memorizing that thing. However, it's not as big and scary as the so-called "I hate math" media would have you believe. Fake News.

meh it's all relative. compared to all the math needed for medicine, that equation is by far the worst. in biophysics, that equation is child's play.

 

[longhaul3]

Probably not strictly necessary for now, but heads up—it will come up again in med school, at least in your first semester/year of basic science.

Really not that complicated but worth learning. It's just the Nernst equation like was noted above. You will need it to understand transepithelial transport and renal physiology, pathophysiology of CF and mechanism of diuretics.

Edit: someone will probably come and say "I am the chair of nephrology at Prestigious School of Medicine and I don't use it" but I guarantee you will at least see it again.

 

[libertyyne]

I guess I must be really dumb because i forgot the nernst equation and the henderson hasselbach equation already.

 

[longhaul3]

I guess I must be really dumb because i forgot the nernst equation and the henderson hasselbach equation already.

Not saying you need to remember it for the start of med school. You don't need to remember anything.

 

[Lawpy]

Probably not strictly necessary for now, but heads up—it will come up again in med school, at least in your first semester/year of basic science.

Really not that complicated but worth learning. It's just the Nernst equation like was noted above. You will need it to understand transepithelial transport and renal physiology, pathophysiology of CF and mechanism of diuretics.

Edit: someone will probably come and say "I am the chair of nephrology at Prestigious School of Medicine and I don't use it" but I guarantee you will at least see it again.

yeah but who actually uses it in clinical practice? probably no one. the concepts underlying that are important, but using the equation for calculating something is really doubtful.

I guess I must be really dumb because i forgot the nernst equation and the henderson hasselbach equation already.

the Henderson-Hasselbalch equation apparently isn't clinically useful, which is why quick shortcuts were developed to get an intuitive understanding. simplicity seems to be the key for clinical practice.

 

[Matthew9Thirtyfive]

It's just a generalized Nernst!

We get it. You're smart.

 

[freak7]

We get it. You're smart.

I am no such thing! How dare you.