BMW M3

Senior Member
10+ Year Member
5+ Year Member
Oct 19, 2005
347
1
Status
In his neoplasia lecture, goljan mentions something about "AUPA [sic!!!] tumors" i don't know what he is referring to... can anyone point in the in the right direction?

Thanks!
 

osli

Senior Member
10+ Year Member
5+ Year Member
Oct 13, 2005
1,279
6
43
Status
Medical Student
APUD tumors... amine precursor uptake and decarboxylation.
 

DwyaneWade

Reiging *** Cynic
10+ Year Member
May 7, 2006
669
0
NC
Status
Resident [Any Field]
APUD tumors... amine precursor uptake and decarboxylation.
Just a special name for those tumors which make peptides and are mostly of neuroendocrine origin?
 

DragonWell

Moderator Emeritus
10+ Year Member
Nov 20, 2004
1,682
10
45
Status
Attending Physician
Please correct me if I'm wrong, but I believe they are also S-100 antigen positive and usually of neural crest origin, ie a melanoma.
 

DwyaneWade

Reiging *** Cynic
10+ Year Member
May 7, 2006
669
0
NC
Status
Resident [Any Field]
Please correct me if I'm wrong, but I believe they are also S-100 antigen positive and usually of neural crest origin, ie a melanoma.
No that's right. Small cell carcinoma of the lung is also S-100 positive, as is pheo.
 

docmd2010

Senior Member
10+ Year Member
7+ Year Member
Apr 17, 2005
523
2
Status
apud tumors are tumors of neural crest origin. they stain with s-100 because of the neurofilaments. another example is carcinoid tumors.
 

osli

Senior Member
10+ Year Member
5+ Year Member
Oct 13, 2005
1,279
6
43
Status
Medical Student
Just a special name for those tumors which make peptides and are mostly of neuroendocrine origin?
Yup. APUD stuff is secretory, making the majority of the bodies' peptide hormones.