Has anyone compounded LCD in triamcinolone lately??

[clachan3]

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Our pharmacy reference books suck Does anyone have a compounding recipe book with LCD 10% in triamcinolone 0.1% in it? I guess I am supposed to use coal tar usp solution for this, but I have no idea where to start I still can't find anything online for some reason. I would really appreciate it if someone could share this information with everyone here
Pretty Please ~ & Thank you ~

 

[Old Timer]

Our pharmacy reference books suck Does anyone have a compounding recipe book with LCD 10% in triamcinolone 0.1% in it? I guess I am supposed to use coal tar usp solution for this, but I have no idea where to start I still can't find anything online for some reason. I would really appreciate it if someone could share this information with everyone here
Pretty Please ~ & Thank you ~

P.S. I am really hoping that I'm not the only one not knowing how to mix this ...

LCD is Liquor Carbonis Detergens or Coal Tar Solution USP which contains 20% Coal Tar in an alcoholic solution.

The preparation is very simple:

• Weigh the TMC
• Measure the Coal Tar
• Place the TMC on your ointment slab
• Slowly levigate the LCD into the TMC
• Transfer to an ointment jar.

Creams are better than ointments as 10% LCD in ointment formulations tend to lay on the top of the ointment and don't always remain dispersed throughout the preparation.

 

[Praziquantel86]

First, are you making an ointment or suspension? If ointment, see OldTimer. If suspension, see below

Weigh the correct amount of triamcinolone (base, I'm assuming) and place in a mortar. Measure out the correct amount of coal tar, and triturate the triamcinolone powder. Quantitatively transfer to a precalibrated container, QS with distilled water.

Label shake well, may stain clothing, smells like anus.

 

[Old Timer]

First, are you making an ointment or suspension? If ointment, see OldTimer. If suspension, see below

Weigh the correct amount of triamcinolone (base, I'm assuming) and place in a mortar. Measure out the correct amount of coal tar, and triturate the triamcinolone powder. Quantitatively transfer to a precalibrated container, QS with distilled water.

Label shake well, may stain clothing, smells like anus.

Have you ever made the suspension? In almost 30 years, I have never seen this.....

 

[Praziquantel86]

I did once, for seborrheic dermatitis.

 

[clachan3]

First, are you making an ointment or suspension? If ointment, see OldTimer. If suspension, see below

Weigh the correct amount of triamcinolone (base, I'm assuming) and place in a mortar. Measure out the correct amount of coal tar, and triturate the triamcinolone powder. Quantitatively transfer to a precalibrated container, QS with distilled water.

Label shake well, may stain clothing, smells like anus.

Wow, I didn't even know there was a suspension. . . Thanks for the info

 

[clachan3]

LCD is Liquor Carbonis Detergens or Coal Tar Solution USP which contains 20% Coal Tar in an alcoholic solution.

The preparation is very simple:

• Weigh the TMC
• Measure the Coal Tar
• Place the TMC on your ointment slab
• Slowly levigate the LCD into the TMC
• Transfer to an ointment jar.

Creams are better than ointments as 10% LCD in ointment formulations tend to lay on the top of the ointment and don't always remain dispersed throughout the preparation.

Oldtimer, if I remember correctly, the prescription only said LCD 10%/TMC 0.1% ointment; 4oz (or something like that).

• I am guessing 10% LCD in 4oz of TMC/final product.
• LCD amount needed to make 10%= 0.1 x 4oz x 28.35g/oz =11.34g
• LCD comes in 20% equals 20 x 10mg/ml = 200mg/ml
• I will need 11.34g x ml/0.2g= 56.7ml of 20% LCD???

That looks really wrong... How am I supposed to put almost 2 fl oz of LCD in 4oz ointment???

I'm an idiot 🙁