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Dec 5, 2013
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I am struggling with revising glomerulonephritis. I have in my notes, which i have compiled from my lectures:

Proliferative Glomerulonephritis

  1. Focal proliferative-mesangial IgA disease
  2. Focal necrotising (crescentic) glomerulinephritis
  3. Diffuse proliferative-postinfective glomerulonephritis
  4. Membrano-proliferative nephritis
Non-proflierative glomerulonephritis

  1. Minimal change disease
  2. Focal glomerulonephritis
  3. Membranous nephropathy
At least for the proliferative GN, I can't see the difference!!

I know postinfective GN usually occurs after infection, usually laryngeal or skin. I know focal necrotising usually occurs with autoimmune conditions. But at least for the other 2, I am stuck.


I just get confused with them all.

And what is the difference between nephritis and nephropathy?

Please help!
 

nephappl

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Focal means not all the glomerulli are involved by either proliferation, necrosis etc
Segmental means that only one segment of each glomerulus is involved
Membarno proliferative is a pecial form of nephritis where you see masangial proliferation + endocapillary proliferation usually in a lobular way (used to be called lobular glomerulonephritis) and has different etiologies
Focal proliferatie IgA is one of the histologic variants of Ig A Nephropathy
You in general name the nephritis based on its histology and the kind deposits present on immunofluorescence
Nephropathy is a general non s[pecific term for kidney disease
Nephritis is a kidney disease where inflammation is the predominant finding and pathogenetic mechanism
 

gutonc

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The IM and subspecialty forums are not an appropriate place for homework help. Closing.
 
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