High Yield pearls not found in First AID

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neopentanol

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I'll start and hope this takes off.

Campylobacter jejuni: Very common cause of enteritis that ranges from mild to bloody diarrhea. Gram (-) oxidase (+) rod found in poultry and animal feces that is self limited or treated with erythromycin. Commonly leads to guillain barre.

does not survive alkali test (vs. Vibrio, which does)
 
Correct me if I may be wrong on this but different strains of E.Coli have different mechanisms for producing diarrhea -
ETEC - Increases cAMP
EHEC - Is Shiga like toxin - so inactivates 60S Ribosome

Above detail is in First Aid but a little unclear

Also, +ve SSRNA - Eg: Echovirus - have polycistronic mRNA. i.e cleave one mRNA molecule to obtain different proteins. (I think i read this in uworld and very low% of people had this correct..umm including myself 😛
 
yeah its kind of hard to pick out High Yield pearls considering I've annotated my entire book with stuff I considered high yield but if I think of something just earth shatteringly high yield I'll make sure to post it
 
My understanding is that Campylobacter doesn't commonly lead to GBS, it's a rare progression, although Campylobacter is the most common cause of GBS?
 
That may be true, but regardless Guillain-Barre is a highly tested concept and a lot of the time they are going to give you clues to the effect of "two weeks after a diarrheal illness patient presents with lower extremity weakness blah blah blah" so its a good thing to know. Just b/c something isn't common doesn't mean they don't test it a lot. Viral upper respiratory infections are about 10000x more common, but I bet you are more likely to see a question on guillain-barre than uncomplicated URI
 
Ok I got one: I wont say where these came from b/c theres a big disclaimer on this certain source of questions that warns against reproducing information 'here-in'


When normal treatments for Psoriasis fails, two systemic therapies you can try are:

1) Acitretin
2) Calcipotriene


I'll let you guys look up what they are , I couldnt find a single mention of either in FA. But now both have come up in questions twice for me over the last 3 weeks.
 
Just about anything you can think of in GI. Seriously, the GI section of FA is pretty lacking.


ditto on embryo... I know Taus said embryo in FA is enough but my embryo section is absolutely LITTERED with extra material. Although in his defense, I'm noticing that stuff show up later on in the theme sections sometimes.


also, anyone else get pissed off @ FA's index.. half the crap I try to look up is not in the index.. makes finding stuff a #$#&($#
also, UW SUCKS at categorizing their questions lol,, i never go to the section they list to annotate.
 
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Correct me if I may be wrong on this but different strains of E.Coli have different mechanisms for producing diarrhea -
ETEC - Increases cAMP
EHEC - Is Shiga like toxin - so inactivates 60S Ribosome
ETEC has Stable Toxin and Labile Toxin. ST causes increased gyanylate cyclase, and LT causes increases adenylate cyclase. So more cAMP and cGMP, and both contribute to the non-bloody diarrhea... that was my understanding at least
 
Ok I got one: I wont say where these came from b/c theres a big disclaimer on this certain source of questions that warns against reproducing information 'here-in'


When normal treatments for Psoriasis fails, two systemic therapies you can try are:

1) Acitretin
2) Calcipotriene


I'll let you guys look up what they are , I couldnt find a single mention of either in FA. But now both have come up in questions twice for me over the last 3 weeks.

I know! 😀
 
Here is a high yield question I got from Kaplan Qbank a minute ago, I'll summarize.

Which blood pressure would be found in Aortic Regurgitation?

A. 170/100

B. 160/50

C-E- Dumb answers.


Honestly, how am I expected to know that? I would love to do a poll to see how many people can get this right, even with unlimited access to the freaking internet.
 
Here is a high yield question I got from Kaplan Qbank a minute ago, I'll summarize.

Which blood pressure would be found in Aortic Regurgitation?

A. 170/100

B. 160/50

C-E- Dumb answers.


Honestly, how am I expected to know that? I would love to do a poll to see how many people can get this right, even with unlimited access to the freaking internet.

I vote B.. i remember 'bounding pulses' thats all lol
 
Here is a high yield question I got from Kaplan Qbank a minute ago, I'll summarize.

Which blood pressure would be found in Aortic Regurgitation?

A. 170/100

B. 160/50

C-E- Dumb answers.


Honestly, how am I expected to know that? I would love to do a poll to see how many people can get this right, even with unlimited access to the freaking internet.

ssup brotha

With aortic regurg you have widened pulse pressure. Systolic: 160 (no probs), diastolic: 50 why? because when there is a regurg the aorta is basically open the left ventricle (the diastolic pressure in the left ventricle is around 12) so there is a drop in pressure.
 
Yeah, I knew it was going to be bounding pulses. But I was just a little confused because I thought both of those could be considered bounding. A pulse pressure of 70 (170/100) is pretty dang high as well.

Anyways, sorry to waste time with this.
 
Yeah, I knew it was going to be bounding pulses. But I was just a little confused because I thought both of those could be considered bounding. A pulse pressure of 70 (170/100) is pretty dang high as well.

Anyways, sorry to waste time with this.


Yeah the key is that the DBP usually drops because some of the blood is flowing back into the LV from the Aorta (so less blood being forced forward through the aorta/arterial system than usual).
 
Yeah the key is that the DBP usually drops because some of the blood is flowing back into the LV from the Aorta (so less blood being forced forward through the aorta/arterial system than usual).

Well dang it. Here I am trying to mock Kaplan and I end up looking like the idiot. I've done too many questions today. My brain is fried.

I still don't like Kaplan though.
 
Well dang it. Here I am trying to mock Kaplan and I end up looking like the idiot. I've done too many questions today. My brain is fried.

I still don't like Kaplan though.


Hey man, I don't like to get in the way of Kaplan mocking (I've done my fair share). But yeah, I remember reading this in Goljan (although to be quite honest, I can't say I might not have had the same reaction you did when getting to that question).
 
Well dang it. Here I am trying to mock Kaplan and I end up looking like the idiot. I've done too many questions today. My brain is fried.

I still don't like Kaplan though.

Just use this opportunity to learn.

I'd concur with "B" because you just gotta see which one has the highest pulse pressure. Typically stroke volume would be very high because End diastolic volume is high. Stroke volume determines your systolic blood pressure. Because there's regurgitation, the good part of diastolic blood pressure goes straight back into the heart.

Even Uworld has a few questions just like that, that you just look at and think :wtf:
 
dont worry, i hated kaplan too.. i returned it 2 days after I got it and lost 30% of my purchase price. I got USMLERx for the school year instead.. way better than Kaplan..

UW is king though
 
Ok I got one: I wont say where these came from b/c theres a big disclaimer on this certain source of questions that warns against reproducing information 'here-in'


When normal treatments for Psoriasis fails, two systemic therapies you can try are:

1) Acitretin
2) Calcipotriene


I'll let you guys look up what they are , I couldnt find a single mention of either in FA. But now both have come up in questions twice for me over the last 3 weeks.
Acetretin is a systemic Vitamin A analog, but Calcipotriene (AKA calcipotriol) is a topical vitamin D anaolog. I know where these came from and I was like, Where-TF did they pull these out of (though I managed to guess correctly!)
 
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