EctopicFetus said:
Too funny..
http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/202602.html
Anyways it CAN cause SEs like Bone marrow suppression but.... this is not a common effect...
As for why I wont take AZT or anything else you are mixing 2 things.. I never said it doesnt have SEs rather that it is NOT an immunosuppresent. Dont confuse the issue cause you have no idea what you are talking about.
Its a common trick used by people who make nonsensical arguments you dont answer the real issue but rather you try to change it a little to muddy the waters.. Nice try,..
AZT was originally developed as an anti-cancer agent until it proved too harmful. Years later it was resurrected as an anti HIV and AIDS drug.
Studies of AZT treatments have confirmed cytotoxicity of DNA chain terminators (Oddone et al., 1993; Tokars et al., 1993; Lenderking et al., 1994; Lundgren et al., 1994; Seligmann et al., 1994). One study observed a 25% increased mortality (Seligmann et al., 1994), and another a 4.5-fold higher annual AIDS risk and a 2.4-fold higher annual death risk in AZT-treated HIVpositive hemophiliacs compared to untreated controls (Goedert et al., 1994).
Oddone, E.Z., P. Cowper, J.D. Hamilton, D.B. Matchar, P. Hartigan, G. Samsa, M. Simberkoff & J.R. Feussner, 1993. Cost-effectiveness analysis of early zidovudine treatment of HIV infected patients. Br. Med. J. 307: 1322-1325.
Tokars, J.I., R. Marcus, D.H. Culver. C.A. Schable, E.S. McKibben, C.I. Banden and D.M. Bell, 1993. Surveillance of HIV Infection and Zidovudine Use among Health Care Workers after Occupational Exposure to HIV-infected Blood. Ann. Intem. Med. 118: 913-919.
Lenderking, W.R., R.D. Gelber, D.J. Conon, B.E Cole, A. Goldhirsch, P.A. Volberding & M.A. Testa, 1994. Evaluation of the quality of life associated with Zidovudine treatment in asymptomatic Human Immunodeficiency Virus Infection. N. Engl. J. Med. 330: 738-743.
Lundgren, J.D., A.N. Philips, C. Pedersen, N. Clumeck, J.M. Gatell, A.M. Johnson, B. Ledergerber. S. Vella & J.O. Nielsen. 1994. Comparison of long-term prognosis of patients with AIDS treated and not treated with Zidovudine. J. Am. Med. Assoc. 271: 1088-1092.
Seligmann, M., D.A. Warrell, J.-P. Aboulker, C. Carbon, J.H. Darbyshire, J. Dormont, E. Eschwege, D.J. Gitling, D .R. James, J.-E. Levy, P.T.A. Peto, D. Schwarz, A.B. Stone, I.V.D. Weller, R. Withnall, K. Gelmon, E. Lafon, A.M. Swart, V.R. Aber, A.G. Babiker, S. Lhoro, A.J. Nunn & M. Vray, 1994. Concorde: MCR/ANRS randomised double-blind controlled trial of immediate and deferred zidovudine in symptom-free HIV infection. Lancet 343: 871-881.
Goedert, J.J.. A.R. Cohen, C.M. Kessler, S. Eichinger, S.V. Seremetis, C.S. Rabkin, EJ. Yellin, P.S. Rosenberg & L.M. Aledort. 1994. Risks of immunodeficiency, AIDS, and death related to purity of factor VIII concentrate. Lancet 344: 791-792.