Step I how does SNRI and anti-epileptics cause hyponatremia?

Started by osprey099
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osprey099

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I just got a question wrong where I had to realize that hyponatremia can be induced by venlafaxine (SNRI) and gabapentin (anti-epileptic). The explanation didn't say the mechanism behind it. Does anyone here know? Nothing really shows up online.
 
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osprey099 said:
I just got a question wrong where I had to realize that hyponatremia can be induced by venlafaxine (SNRI) and gabapentin (anti-epileptic). The explanation didn't say the mechanism behind it. Does anyone here know? Nothing really shows up online.
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My speculation would have to do with serotonin's effect on GI cells. Possibly diarrhea induced hyponatremia? That seems like a stretch to me but maybe someone can confirm.
 
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