Vitalsource (textbooks on the computer) is an interesting subject. I love them. I hate paying for them. ($1500 would be nice - I think we pay more than $3000 per year...) I worry about what will happen to all my notes/highlights when a new edition of the book comes along and the old edition "disappears"...
A lot of people who initially are skittish about the idea of digital textbooks soon find that most of what you learn at school comes from sources other than reading textbooks. Most of our material, for example, comes almost exclusively from professors' power point slides. Most of the time, the textbook is just for reference which works out really well to have in a searchable format.
The search capabilities are awesome. You can quickly review all your notes and you can highlight different things (like exam, important, etc.)
IMO, Vitalsource is an incredible luxury. If I had the choice of buying hard copies or Vital Source, I would pick up the real books and save myself the $8,000 over the course of school, but since I don't have a choice, the lap of luxury isn't all that bad.