Hypercalcemia
Started by superoxide
Upon a quick search (hypercalcemia), Wikipedia says hyperthyroid --> high bone turnover rate, which in turn would lead to a hypercalcemic state. That might give you something to go on?
Initially your question boggled me too, since hyperthyroid may lead to more calcitonin which would have the opposite effect, but apparently the bone turnover cancels out/overrules the calcitonin perhaps?
Initially your question boggled me too, since hyperthyroid may lead to more calcitonin which would have the opposite effect, but apparently the bone turnover cancels out/overrules the calcitonin perhaps?
yup, i found this on pubmed:
"Hyperthyroidism is often associated with hypercalcemia which is provoked by osteoclastic activity of the thyroid hormones."
jeez, who knew?😳
"Hyperthyroidism is often associated with hypercalcemia which is provoked by osteoclastic activity of the thyroid hormones."
jeez, who knew?😳
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Not sure if this is correct, but hyperthyroidism leads to an increased metabolic rate and increased basal body temperature. IL-1 is an endogenous pyrogen that increases basal body temperature. IL-1 is also osteoclast activating factor which would of course lead to hypercalcemia.
Anyone want to check if IL-1 is the mechanism by which thyroxine increases basal body temp?
Anyone want to check if IL-1 is the mechanism by which thyroxine increases basal body temp?
^^^I saw that part on Wiki, but couldn't remember (yes OR no) if we covered it in class and didn't want to throw that out there and look like a fool. It does sound vaguely familiar though.
IL-1 huh? I may have to look into that later today (as a procrastination device, of course)
IL-1 huh? I may have to look into that later today (as a procrastination device, of course)
i learned about the IL-1 (osteoclast activating factor) relationship from goljan audio lectures. I never even thought about that when thinking about hypercalcemia...and my exam is 2 days away
