Quantcast

hyperkalemia and acidosis

This forum made possible through the generous support of SDN members, donors, and sponsors. Thank you.

usmletoo

Full Member
10+ Year Member
Joined
Mar 19, 2009
Messages
40
Reaction score
0

Members don't see this ad.
please need help understanding this
So both acute and chronic metabolic acidosis have hyperkalemia- but in acute not enough time to fully compensate low renal excretion of K and K balance is positive - in chronic enough time to compensate lots of Hco3 are being made alot of H+ are pumped this neutralizes the charges in the membrane - this stops attracting H+ and K+ , so no secretion ...so what I don't understand is why renal excretion of K is high and the K balance is negative...
can someone explain PLEASEEE
thanks
 

kunfu

Full Member
10+ Year Member
7+ Year Member
Joined
Feb 28, 2007
Messages
149
Reaction score
0
I'm having some trouble understand exactly what your asking. But it seems like you may be forgetting a key fact. The hyperkalemia from acidosis is the result of a shift of K out of the cells into the plasma, in exchange for H ions. Hence if renal excretion of K is increased it is possible to have a negative K balance while still having a high level of K in the blood (Hyperkalemia).
 

usmletoo

Full Member
10+ Year Member
Joined
Mar 19, 2009
Messages
40
Reaction score
0
thank you for taking the time to answer my question

so I agree with you - but why does it say there- acute- low K excretion / positive balance- and Chronic - high K excretion / negative balance?
help pleaseee
thanks
 

Attachments

  • scan0001.pdf
    719.7 KB · Views: 55
  • scan0002.pdf
    480.1 KB · Views: 35

kunfu

Full Member
10+ Year Member
7+ Year Member
Joined
Feb 28, 2007
Messages
149
Reaction score
0
thank you for taking the time to answer my question

so I agree with you - but why does it say there- acute- low K excretion / positive balance- and Chronic - high K excretion / negative balance?
help pleaseee
thanks

Im not sure but my bet is that in a chronic condition you have more K building up in the plasma, as more and more K leaves the cell. As a result K excretion increases to maintain K levels in blood. Remember K levels must be kept relatively constant to avoid arrhythmias and all sorts of problems. In an acute case the K levels in the blood havent risen enough to cause significantly increased secretion.
 
Top