When I interviewed last year the only reason it came up was when they asked me, "What do you feel is a weakness in your application?"
And I told them that I didn't have any research experience, primarily because I double majored in two non-related fields and wasn't interested in anything at my school. It depends on the school how much emphasis they put into it, but if/when it comes up again, I will be perfectly honest and say I would rather spend my time working directly with patients than in a lab.