Immunology

[BestDoctorEver]

Which of the following statements about MHC I and MHC II is NOT true?


A. MHC I is found on antigen presenting cells.

B. MHC II is found on all nucleated cells.

C. MHC I presents peptide fragments to cytotoxic T cells via the CD8 receptor.

D. MHC II presents peptide fragments to helper T cells via the CD4 receptor

I got the right answer because I know C and D are true but I did not know the difference between A and B...It was a 50/50 between A and B and I ended up choosing B, which is right...Is the MCAT going be that specific? Can someone elaborate on A and B?





edit......

---

Members don't see this ad.

 

[FutureDoctor503]

Which of the following statements about MHC I and MHC II is NOT true?


A. MHC I is found on antigen presenting cells.

B. MHC II is found on all nucleated cells.

C. MHC I presents peptide fragments to cytotoxic T cells via the CD8 receptor.

D. MHC II presents peptide fragments to helper T cells via the CD4 receptor

I got the right answer because I know C and D are true but I did not know the difference between A and B...It was a 50/50 between A and B and I ended up choosing B, which is right...Is the MCAT going be that specific? Can someone elaborate on A and B?





edit......

Statement A is correct because MHC I is found on ALL nucleated cells, this includes antigen presenting cells. However, Statement B is incorrect because MHC II is NOT found on ALL nucleated cells; it is only found on antigen presenting cells.

 

[typicalindian]

all nucleated cells(including antigen presenting cells) contain MHC class 1

only antigen presenting cells also have MHC class 2.

 

[BestDoctorEver]

all nucleated cells(including antigen presenting cells) contain MHC class 1

only antigen presenting cells also have MHC class 2.

Will the MCAT be that specific?

 

[typicalindian]

Will the MCAT be that specific?

that is basic immunology, not specific.

 

[Charles_Carmichael]

Think of it like the "rule of 8":

8 x 1 = 8

4 x 2 = 8

The answer should always be 8.

So, MHC I presents to CD8 T-cells (8 x 1 = 8) and MHC II presents to CD4 T-cells (4 x 2 = 8).

 

[Temperature101]

that is basic immunology, not specific.

Wow...EK bio does not even talk about MHCI and MHCII....I better check the AAMC guide again.

 

[SaintJude]

Think of it like the "rule of 8":

8 x 1 = 8

4 x 2 = 8

The answer should always be 8.

So, MHC I presents to CD8 T-cells (8 x 1 = 8) and MHC II presents to CD4 T-cells (4 x 2 = 8).

That's brilliant. I'll remember that even for medschool. You really could write a MCAT bio prep book better anyone out there at the moment.

 

[MedPR]

Think of it like the "rule of 8":

8 x 1 = 8

4 x 2 = 8

The answer should always be 8.

So, MHC I presents to CD8 T-cells (8 x 1 = 8) and MHC II presents to CD4 T-cells (4 x 2 = 8).

This is true and is commonly taught in immunology/physiology classes, but it doesn't help you answer this question if you already know C and D are wrong.

 

[MedPR]

Will the MCAT be that specific?

that is basic immunology, not specific.

All you really need to know to answer this question is "MHC I is found an all nucleated cells." With that in mind, you can immediately pick B and not even look at C or D.