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Immunology

BestDoctorEver

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  1. Medical Student
    Which of the following statements about MHC I and MHC II is NOT true?


    A. MHC I is found on antigen presenting cells.

    B. MHC II is found on all nucleated cells.

    C. MHC I presents peptide fragments to cytotoxic T cells via the CD8 receptor.

    D. MHC II presents peptide fragments to helper T cells via the CD4 receptor

    I got the right answer because I know C and D are true but I did not know the difference between A and B...It was a 50/50 between A and B and I ended up choosing B, which is right...Is the MCAT going be that specific? Can someone elaborate on A and B?





    edit......
     
    Last edited:

    FutureDoctor503

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    Apr 13, 2011
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    1. Pre-Medical
      Which of the following statements about MHC I and MHC II is NOT true?


      A. MHC I is found on antigen presenting cells.

      B. MHC II is found on all nucleated cells.

      C. MHC I presents peptide fragments to cytotoxic T cells via the CD8 receptor.

      D. MHC II presents peptide fragments to helper T cells via the CD4 receptor

      I got the right answer because I know C and D are true but I did not know the difference between A and B...It was a 50/50 between A and B and I ended up choosing B, which is right...Is the MCAT going be that specific? Can someone elaborate on A and B?





      edit......



      Statement A is correct because MHC I is found on ALL nucleated cells, this includes antigen presenting cells. However, Statement B is incorrect because MHC II is NOT found on ALL nucleated cells; it is only found on antigen presenting cells.
       
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      SaintJude

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        Think of it like the "rule of 8":

        8 x 1 = 8

        4 x 2 = 8

        The answer should always be 8.

        So, MHC I presents to CD8 T-cells (8 x 1 = 8) and MHC II presents to CD4 T-cells (4 x 2 = 8).

        That's brilliant. I'll remember that even for medschool. You really could write a MCAT bio prep book better anyone out there at the moment. :thumbup:
         

        MedPR

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        1. Pre-Podiatry
          Think of it like the "rule of 8":

          8 x 1 = 8

          4 x 2 = 8

          The answer should always be 8.

          So, MHC I presents to CD8 T-cells (8 x 1 = 8) and MHC II presents to CD4 T-cells (4 x 2 = 8).

          This is true and is commonly taught in immunology/physiology classes, but it doesn't help you answer this question if you already know C and D are wrong.
           
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