Absolutely.
I think the patient tolerance is my typical guide. I don't like things that bleed a lot or take awhile or need sutures, cautery, etc in the office if it's not absolutely necessary (ingrowns never are emergent despite what the NPs in Urgent Care seem to think). I used to think I could just tell who the patients that would be ok to do 3:1 lesion excis, sharp ingrown, aggressive wound care with a fair amount of bleeding, lac repair without a visual barrier, etc on... but then I had enough 'tough' looking/sounding patients who still syncopized and slumped out of the chair or even came very close to having to be sent to ER for eval of basically glorified panic attacks. I guess that stuff can happen even from suture removal or injections, but it seems more common with longer or more bloody procedures in my exp. Even if the patient is ok, I also don't love it when I've clearly alarmed my new MAs, hah. Plus, as if the procedure didn't get me an appoint slot or two behind, the damage control for the fainting and sending your MA for orange juice and then checking on them again gets your clinic flow even a bit more backed up (kidding... kinda).
Toe amps are debatable depending on the cellulitis/abscess and urgency, but I like to cut the mid or prox phalanx as opposed to disarticulations... so that's an OR thing in my hands also and not bedside/office unless some rare circumstance (maybe huge pt deductible and/or bad cellulitis pt in office... where I may open amp and then send to hospital for IV, closure in OR after office or next morning). I do tendonotomies on lesser digits in office if I think they might work, but I use 18ga and that's over in less than an minute with a pressure wrap, no sutures and basically less time and bleeding than ingrown. I realize I'm on the conservative end. Conversely, I think some other guys still do plantar fascia releases, MIS, 3-stab TALs, and other stuff in office, so again, it's all about personal preference. As long as nobody's crashing off the guard rails of local standard of care (or sterility, as you said), it's personal pref.
I will do some reasonably messy or painful I&Ds, reductions, lac repairs, etc at ER or hospital bedside +/- IV sed, but I feel that stuff is immediately necessary for perfusion/sepsis/etc reasoning... I don't feel it's really a choice unless you could get to OR immediately.