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They are real alright and the dynamic interaction between the head and the gut and the bacteria that live there is quite fascinating. At this point in time, treating the psychological component has been demonstrated to be most effective. The degree to which the patient is able to understand that and actively cope with that aspect as opposed to continue medical tests, procedures, and medications to try and fix it or the degree to which there is secondary gain such as disability is very predictive of outcome. It definitely isn't black and white although the patients with that type of thinking also seem to struggle more.
Speaking of something like IBS and dynamic interaction between head and gut+bacteria, I've always found it interesting that so many patients with eating disorders end up diagnosed with IBS. It makes me wonder if it's more a mechanical/physical thing at play, or if it's more psychological, or a combination of both. I can understand IBS, or IBS type symptoms occurring in someone when they're still actively disordered, but it seems a little odd to me that it seems to so often persist even after someone has been stable in recovery for a number of years.