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Is Fo/F1 ATPase same thing as ATP synthase?

Discussion in 'MCAT Study Question Q&A' started by m25, Sep 26, 2014.

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  1. m25

    m25

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    May 28, 2014
    Is Fo/F1 ATPase same thing as ATP synthase?
    If so, how can this be true, given the fact that whenever something is named "ATPase," it uses up ATP, but it is actually synthesizing ATP in this case?
     
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  3. Cawolf

    Cawolf 2+ Year Member

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    F ATPase is as you said, just another name for ATP synthase.

    An ATPase can work both ways - anabolic or catabolic. In the case of ATP synthase it uses the gradient to do work, but it can also use ATP to drive a gradient.

    In general, an ATPase can work either way.
     
  4. m25

    m25

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    May 28, 2014
    Oh I see. Does that mean ATP synthase can also work both ways?
     
  5. Cawolf

    Cawolf 2+ Year Member

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    Feb 26, 2013
    Yes.

    A common example is seen in flagellated anaerobic prokaryotes. The complex catalyzes ATP hydrolysis to generate a proton gradient. The gradient then powers the flagellum.
     

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