It's fine to ask about the importance of something, but it gets annoying when people are only concerned about the grade (pre-meds are the worst at this).
I think it would be cool if more people would ask questions just out of curosity, to deviate from the notes more often and talk about recent findings and such.
Seems a lot of lectures aren't even worth attending/ listening to since they just read from the powerpoint and nobody brings up anything new.
Ah but maybe I'm just used to smaller classrooms where this more feasible.