J&J on the move, new Antibiotic approved

Started by Epic
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I'm so sad...I try to edumacate you young folks..and some old farts.. and newbies come on board and think I'm loud mouthed.. wait, they're right.. :meanie:
 
It says it has activity against c. diff....but wouldn't you be worried about it causing c. diff since it is so broad spectrum?
 
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KARM12 said:
It says it has activity against c. diff....but wouldn't you be worried about it causing c. diff since it is so broad spectrum?
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You asking me?

Why don't you tell me...
 
I am actually not sure....that is what I would think. You are killing off a lot of that gut bacteria.
 
KARM12 said:
I am actually not sure....that is what I would think. You are killing off a lot of that gut bacteria.
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but we already have with ertabpenm, imipenem, and meropenem...
 
KARM12 said:
I know all about C. Diff...I could smell it a mile away. Everyone at the VA had it. Not good.
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Oh is that right.... so what's caused all those C.Diff outbreak recently
 
Epic said:
:meanie::meanie: You're scrambling.. yes, dirty hands had a lot to do with it... gather your thoughts and organize it..
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I thought I finished my rotations....

C. Diff has spores that are stable on surfaces...which is why proper contact precautions and disinfection of the patient room are necessary.
 
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This article is too large for me to load here..

If you have a subscription to CID...then more better... but here is a good read.

Emergence of Fluoroquinolones as the Predominant Risk Factor for Clostridium ...
Jacques Pépin; Nathalie Saheb; Marie-Andrée Coulombe; Marie-Eve Alary; et al
Clinical Infectious Diseases; Nov 1, 2005; 41, 9; Research Library
 
Epic said:
how can we believe that? And how does that translate to clinical outcomes?
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It's a carbapenem...broadest spectrum spectrum beta-lactams...good DOC for gram-neg when resistance is an issue. If it really is more potent than Meropenem, we're probably talking MIC's of 4 rather than 8+. Seems like it's main place will be with serious nosocomial infections where resistance is an issue.
 
SpirivaSunrise said:
It's a carbapenem...broadest spectrum spectrum beta-lactams...good DOC for gram-neg when resistance is an issue. If it really is more potent than Meropenem, we're probably talking MIC's of 4 rather than 8+. Seems like it's main place will be with serious nosocomial infections where resistance is an issue.
Click to expand...

Why not keep using Imipenem or Meropenem
 
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Sorry...work called me and told me I didn't have to come in today...so I went back to bed.... Where were we?
 
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