Lda

[steppingstone]

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can someone please explain what LDA does/ what common reactions is it found in?

also, for E2, when there isn't a bulky base...does it follow mark addition?

 

[IsaacYankem]

LDA is a strong base used to remove alpha-hydrogens in many ketone/aldehyde alpha addition reactions.

E2 reactions go markovnikov if no bulky base is present and the more substituted side has an anti-periplaner H to leave.

 

[steppingstone]

Thank you!