I currently usually use a standard 16G needle to draw up propofol (haven't seen those "spikes" since residency) and once in a while I'll see a tiny gray piece of the rubber vial stopper in the drug that I've drawn up. I'll then either try to squirt the piece out or toss the entire syringe. But I wonder how many times I miss some small (or even microsopic) fragments of rubber that are being injected intravenously. Anyone else notice this? What do I do without those spikes that have the filter and what about all the other drugs that we draw up. Is anyone simply popping the tops from all vials first?