Loop of Henle

[Jo07]

Would anyone care to explain the Loop of Henle and why the descending branch is more concentrated but permeable to water and vice versa for the ascending loop?

I'm really confused.

Thanks!

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[topdent1]

Here is my understanding.

Going down the loop on Henley, the membrane is permeable to water. Thus, water leaves leaving ions and other solutes. Going up the loop of henle, the membrane is permeable to ions and other solutes. Thus, ions and solutes leave. Because both water and solute have left, the concentration is still constant.

Hope that helps

 

[Mstoothlady2012]

Would anyone care to explain the Loop of Henle and why the descending branch is more concentrated but permeable to water and vice versa for the ascending loop?

I'm really confused.

Thanks!

descending loop - permeable to water...hence passive flow of water out of the tube which will make the urine more concetrated.

ascending loop - impermeable to water so no water movement, but active/passive movement of salts out of the tube...hence will make the urine more dilute

Then it (dilute) enters collecting tube..which has concentrated fluid surrounding it, hence osmosis occur higher conc (urine which is dilute) to lower conc (interstitial fluid which is conc).

Thus the urine that finally enters the pelvis is concentrated.

 

[Jo07]

Thanks guys!

Maybe you can also answer this question...

Where do B-cells develop? Destroyer says fetal liver and spleen. Q 70 . But I was looking at other places that say B cells develop in bone marrow. Ideas?

 

[Mstoothlady2012]

Thanks guys!

Maybe you can also answer this question...

Where do B-cells develop? Destroyer says fetal liver and spleen. Q 70 . But I was looking at other places that say B cells develop in bone marrow. Ideas?

bone marrow

 

[Lonely Sol]

Thanks guys!

Maybe you can also answer this question...

Where do B-cells develop? Destroyer says fetal liver and spleen. Q 70 . But I was looking at other places that say B cells develop in bone marrow. Ideas?

B-cell develop in the liver and spleen in the fetus not in adult

Well, spoecifically blood in produced in the liver for fetus

 

[Jo07]

so for adults it's bone marrow?

 

[Lonely Sol]

so for adults it's bone marrow?

Yea for adults, B-cell develop and mature in bone marrow, while T cell develop in bone marrow but mature in thymus