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Just missed a UWorld question on this, which was asking where the lowest PVR would be on a graph of lung volumes vs. time.
Their "correct" answer was at the point where FRC was labeled. Their explanation was that this was on the steepest part of the compliance curve??
I chose the point where maximum inspiration was labeled. The explanation said this was incorrect because the air-filled alveoli exerted a collapsing pressure on the vasculature, increasing resistance?
Buy would not air forcing alveoli to expand and vasculature to collapse only be the case if air was actively pumped into the lung under pressure? In normal inspiration, the alveoli are expanded because the lung parenchyma is being actively stretched by thoracic movement. i.e., the expanding alveoli draw in air, instead of the air coming in forcing alveoli to expand. And if the alveoli are being stretched via the parenchyma and not the air pressure inside, then there is tension which pulls on everything embedded in the parenchyma, including vasculature. Shouldn't that increase size and decrease resistance, thus yielding the lowest PVR at maximal inspiration?
In fact, isn't the reason why COPDers breath at an increased FRC and have expanded chests is because by keeping the lung maximally expanded the parenchymal tension pulls on the airways and helps keep them expanded? I can't see why what keeps airways expanded would collapse vasculature.
Anyone have any insight into this? Am I completely crazy? Since the average on this question was only 16%, then either the question is wrong or this isn't something covered well in schools and review books.
Their "correct" answer was at the point where FRC was labeled. Their explanation was that this was on the steepest part of the compliance curve??
I chose the point where maximum inspiration was labeled. The explanation said this was incorrect because the air-filled alveoli exerted a collapsing pressure on the vasculature, increasing resistance?
Buy would not air forcing alveoli to expand and vasculature to collapse only be the case if air was actively pumped into the lung under pressure? In normal inspiration, the alveoli are expanded because the lung parenchyma is being actively stretched by thoracic movement. i.e., the expanding alveoli draw in air, instead of the air coming in forcing alveoli to expand. And if the alveoli are being stretched via the parenchyma and not the air pressure inside, then there is tension which pulls on everything embedded in the parenchyma, including vasculature. Shouldn't that increase size and decrease resistance, thus yielding the lowest PVR at maximal inspiration?
In fact, isn't the reason why COPDers breath at an increased FRC and have expanded chests is because by keeping the lung maximally expanded the parenchymal tension pulls on the airways and helps keep them expanded? I can't see why what keeps airways expanded would collapse vasculature.
Anyone have any insight into this? Am I completely crazy? Since the average on this question was only 16%, then either the question is wrong or this isn't something covered well in schools and review books.