I live in Chicago and I would consider myself a "medical person"... whatever that means. I'm going with Loyola.
I disagree with the poster's claim that Rush is considered to have a "better clinical reputation." I have researched both schools extensively and haven't come across any information that would suggest this. Perhaps he's using anecdotal evidence (e.g. a couple years ago he was accepted by Rush and waitlisted by Loyola). From what I can tell, they seem to be fairly similar (the facilities notwithstanding). Like one poster said before, each has its benefits. If you already have a specialty picked out, look at the match lists or U.S. News rankings.