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Managing Lithium Polyuria?
Started by BobA
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QHS dosing can help some, if you're still treating BID or TID.
1. Make sure it's not DI, and if it is monitor lytes closely.
2. There's a little data on amiloride--
http://www.ncbi.nlm.nih.gov/pubmed/19367330
http://www.ncbi.nlm.nih.gov/pubmed/18596116
http://www.ncbi.nlm.nih.gov/pubmed/12680486
NSAID's (esp cox-2 inhibs) apparently could have a role too, but my understanding of that interaction is a lot fuzzier, and seems to have risks as well.
2. There's a little data on amiloride--
http://www.ncbi.nlm.nih.gov/pubmed/19367330
http://www.ncbi.nlm.nih.gov/pubmed/18596116
http://www.ncbi.nlm.nih.gov/pubmed/12680486
NSAID's (esp cox-2 inhibs) apparently could have a role too, but my understanding of that interaction is a lot fuzzier, and seems to have risks as well.
