Managing Lithium Polyuria?
- Thread starter BobA
- Start date
- Joined
- Apr 22, 2007
- Messages
- 2,387
- Reaction score
- 129
- Points
- 4,671
- Attending Physician
QHS dosing can help some, if you're still treating BID or TID.
- Joined
- Oct 16, 2001
- Messages
- 2,871
- Reaction score
- 1,011
- Points
- 5,316
- Location
- Los Angeles, CA
- Attending Physician
1. Make sure it's not DI, and if it is monitor lytes closely.
2. There's a little data on amiloride--
http://www.ncbi.nlm.nih.gov/pubmed/19367330
http://www.ncbi.nlm.nih.gov/pubmed/18596116
http://www.ncbi.nlm.nih.gov/pubmed/12680486
NSAID's (esp cox-2 inhibs) apparently could have a role too, but my understanding of that interaction is a lot fuzzier, and seems to have risks as well.
2. There's a little data on amiloride--
http://www.ncbi.nlm.nih.gov/pubmed/19367330
http://www.ncbi.nlm.nih.gov/pubmed/18596116
http://www.ncbi.nlm.nih.gov/pubmed/12680486
NSAID's (esp cox-2 inhibs) apparently could have a role too, but my understanding of that interaction is a lot fuzzier, and seems to have risks as well.