Nah.. I'd be happy to review it
Would give me a break from all the lit, and make me feel like I knew something about something for a change
Great thanks.. I'll send them over when I get to my second draft.
seraph made a good point also... according to the NIH's roadmap, you definately need to emphasize the translational nature of your research. Are you looking into some sort of novel bowel research? How is e. coli research gonna be applicable to internal medicine, endoscopy, etc?
So I guess my final advice is.. pander to the translational aspect of your studies.
Well, my first study was on Uropathogenic strain. We found a pilus system that played a previously unknown role in the bacterial efflux from kidney cells (tissue cultures and mouse model).
I'm currently working on Enterotoxigenic e. coli, on different pilus system, trying to elucidate an assembly mechanism for the pilus proteins.
In both cases of human pathogens, the ultimate goal is to find a pilus system that would work as a vaccine candidate. So, that's where the bulk of the translational research would probably lie.
But, on the whole, its important to understand how virulence systems work in pathogens, just to be smart about we go about treating for them. My recent project has some interesting evolution aspects, in that, if the hypothesized mechanism is correct, it could shed some light on how the system evolved. That's interesting to me, personally, because I'm also interested in molecular evolution, though I haven't done any research into that yet. Bacterial evolution is potentially very important to medicine, understanding how virulence systems evolved could help us treat for them.
Perhaps I could work some of the above interests into my MD/PhD essay, while letting my MD essay be more general, less specific, but more of an 'emotional argument'. I suppose that could work.