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- Jan 17, 2017
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Hi everyone. I'm new here so if I have posted in the wrong section I apologise in advance, just let me know so I can change it.
As for my question... well I seem to be having trouble with understanding what happens to the H+ that comes from the acids in metabolic acidosis(e.g ketoacid/lactic acid) as far as I have read it says that the H+ ion combines with HCO3- buffers in the blood plasma and from there goes on to produce H2CO3 and from there H2CO3---> H2O + CO2. Yet everywhere it specifically states that in the absence of carbonic anhydrase the reaction is too slow and that blood plasma does not have Carbonic anhydrase(so then how can it turn H2CO3 into H2O and CO2?). So then what is the journey of that specifc H+ ion from the metabolic acid once it combines with HCO3- to form H2CO3. Is it just filtered in the kidney and released in urine in the H2CO3 form??
As for my question... well I seem to be having trouble with understanding what happens to the H+ that comes from the acids in metabolic acidosis(e.g ketoacid/lactic acid) as far as I have read it says that the H+ ion combines with HCO3- buffers in the blood plasma and from there goes on to produce H2CO3 and from there H2CO3---> H2O + CO2. Yet everywhere it specifically states that in the absence of carbonic anhydrase the reaction is too slow and that blood plasma does not have Carbonic anhydrase(so then how can it turn H2CO3 into H2O and CO2?). So then what is the journey of that specifc H+ ion from the metabolic acid once it combines with HCO3- to form H2CO3. Is it just filtered in the kidney and released in urine in the H2CO3 form??
