Minocycline-induced autoimmune disease

[futuredruggist]

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Does anyone know much about Minocycline-induced autoimmune disease, such as incidence, risk factors, etc?

I know that lupus and arthritis have been seen in people who used Minocycline for several years.

I have already done some literature searches and didn't find much in depth. I'm asking if anyone has first-hand experience with this.

 

[ZpackSux]

No first hand experience since minocycline isn't often used but there are many documented cases of Minocycline induced Lupus and/or auto immune hepatitis... there are tons of information and case studies on the net.

One of the key traits of a sucessful pharmacist is the ability to find information.

 

[futuredruggist]

Thanks for the response.

My understanding is that Minocycline is in fact very commonly used as an acne treatment. Also, I know these autoimmune conditions have been mainly observed in young females. But the articles I've found so far are at least a few years old, so I'm still looking for the most current info.

 

[Aznfarmerboi]

I think a few years old article is still good since it is not a brand new drug or anything. I dont have thomsonhc or lex on me so i cant help you right now.

 

[tussionex]

.

One of the key traits of a sucessful pharmacist is the ability to find information.

you don't always have to know the answers, but you should always know where to look🙂

 

[ZpackSux]

you don't always have to know the answers, but you should always know where to look🙂

isn't that what i just said?

 

[tussionex]

isn't that what i just said?

just saying the same thing and using more words🙂

 

[ZpackSux]

just saying the same thing and using more words🙂

I could use some tussionex right now...

 

[sdn1977]

Personally, I find minocycline the most commonly prescribed tetracycline-type antibiotic prescribed on an outpt basis.

Look at this article & it will provide more references:

"Minocycline Induced Autoimmune Hepatitis & Subsequent Cirrhosis"
Journal of Pediatric Gastroenterology & Nutrition
42(2):232-235, Feb 2006