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westernmed007

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Anyone? I have the toughest time remembering these, also does anyone have a good way to tell neuroleptic malig syndrome from seratonin syndrome from like tyramine crisis symptom wise? They seems so similar....
 

Blesbok

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All TCAs have tri, ipr, or oxepin in them.

I don't have a good one for SSRIs, but could use one if someone comes up with one. All I have is -lopram -oxetine and SeRtralIne

The big difference between serotonin syndrome and neuroleptic malignant syndrome is that neuroleptic malignant syndrome causes muscle rigidity while serotonin syndrome does not.

Tyramine induce hypertension is just that, it doesn't include any of the other stuff as far as i know.
 

blz

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The big difference between serotonin syndrome and neuroleptic malignant syndrome is that neuroleptic malignant syndrome causes muscle rigidity while serotonin syndrome does not.

woa there buddy. seritonin syndrome causes a hypertonicity that isn't that easily distinguished from muscle rigidity. the best way to differntiate that two is by history and physical- SS develops within 24hrs, NMS over days to weeks; SS is hyperreactive so you get tremor, clonus, hyperreflexia while in NMS you get ridigity and bradyreflexia; obv you know what causes each

There's never going to be a question on your test that asks what the diff btw NMS and SS is. They're always going to present it in case form in which it'll be easier to figure out.
 
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7abiby

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Try this:

-SSRIs: a pair of oxes got the flu and sat on a sertra matress
(paroxetine) (fluoxetine) (citalopram) (sertraline)


-TCAs: Doc Amit, the desi, took a north trip

(doxepin) (amitriptyline) (desipramine) (nortriptyline)
You'll have to memorize the two other ones (imipramine & clomipramine)

-MAOs: Tranys have a funnel in their pants
(tranylcypromine) (phenelzine)


I know this is crude but it helped me get those drugs down
 

Blesbok

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Try this:

-SSRIs: a pair of oxes got the flu and sat on a sertra matress
(paroxetine) (fluoxetine) (citalopram) (sertraline)


-TCAs: Doc Amit, the desi, took a north trip

(doxepin) (amitriptyline) (desipramine) (nortriptyline)
You'll have to memorize the two other ones (imipramine & clomipramine)

-MAOs: Tranys have a funnel in their pants
(tranylcypromine) (phenelzine)


I know this is crude but it helped me get those drugs down
I went with you need to funnel the tranny fluid so it doesn't spill. :laugh:
 

osli

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Its not available in the US. I hadn't heard of it either.
Good to know. :)

Hey, you could be my neighbor. I'm one of those osteo people in the city. I don't see how you guys ever study or go to class/labs with D'Bronx pizza across the street... I'm hooked!
 

lilnoelle

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Good to know. :)

Hey, you could be my neighbor. I'm one of those osteo people in the city. I don't see how you guys ever study or go to class/labs with D'Bronx pizza across the street... I'm hooked!
Very cool. I really liked KCUMB. Very nice campus, very happy students (or so they seemed). We would be in the same class if I had chosen to attend there.
I honestly have never been to D'Bronx, although its given to us quite often for lunch meetings.
 

osli

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We're actually all utterly miserable, but they have hidden cameras installed all over campus and if we are caught not putting on the happy show for visitors we are beaten in the dungeon below the anatomy lab. :laugh:

Catered D'Bronx? I'm insanely jealous... we keep getting those generic deli sandwiches that taste same no matter where they come from.
 

osli

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Selegiline is not a TCA, is it?
No, it's a MAOI like the others grouped with it. Selegiline isn't usually lumped in like that though since it is relatively specific for MAO type B; it has traditionally been used for Parkinson's and not depression or psychoses since the high doses needed for effective treatment of depression made hypertensive crises likely. A new transdermal dosing system is available now however that is able to keep blood levels high enough for effective treatment of refractory depression with reduced hypertensive risk.
 

DwyaneWade

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No, it's a MAOI like the others grouped with it. Selegiline isn't usually lumped in like that though since it is relatively specific for MAO type B; it has traditionally been used for Parkinson's and not depression or psychoses since the high doses needed for effective treatment of depression made hypertensive crises likely. A new transdermal dosing system is available now however that is able to keep blood levels high enough for effective treatment of refractory depression with reduced hypertensive risk.

Ah, brain fart here :laugh:

I knew it was used for Parkinson's and that inhibited MAO but I forgot it was an MAO inhibitor....UWorld is eating my brain +pissed+
 

osli

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:laugh:

At least you knew and temporarily forgot. I keep seeing questions in UW that make me go "what the... never even heard of that before!:
 
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