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Are we expected to know anything about specific mutations for the MCAT?
Fragile-X, Kleinfelters, etc?
Fragile-X, Kleinfelters, etc?
Are we expected to know anything about specific mutations for the MCAT?
Fragile-X, Kleinfelters, etc?
im pretty sure you just need to know very basic stuff like missense mutations, nonsensce, frameshift, etc; not specific ones. theyd prob give you that in a passage.
im pretty sure you just need to know very basic stuff like missense mutations, nonsensce, frameshift, etc; not specific ones. theyd prob give you that in a passage.
Yup.
Ok thanks, I think I know those
The only ones that aren't obvious from the name are nonsense and missense, right?
nonsense = indel that produces a stop codon
missense = indel that does not produce a stop codon, but does produce a different AA
silent = indel that produces a different codon that codes for the same AA
Are those correct?
Ok thanks, I think I know those
The only ones that aren't obvious from the name are nonsense and missense, right?
nonsense = indel that produces a stop codon
missense = indel that does not produce a stop codon, but does produce a different AA
silent = indel that produces a different codon that codes for the same AA
Are those correct?
yep and remember that out of those three, nonsense is the most deadly, followed by missence, then silent.
Well, a missense MAY create a nonfunctional protein, while a nonsense will ALWAYS create a nonfunctional protein.