My good buddy Hoffman

[Manyak222]

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Quick question..Hoffman eliminatin always produces terminal alkenes right? Never internal ones?
Anyone know why? Peace out 😎

 

[Manyak222]

ehhh fahgetaboutit, this post never existed kapish?
I found my answer

 

[mightymouse23]

Why? Just want to know to make sure im not getting dummer...

 

[Manyak222]

Lol YOUR not getting any DUMMER man!
Hoffman elimination creates terminal alkenes DO TOO steric effects. I have educated thou! Now call me jesus

Why? Just want to know to make sure im not getting dummer...

 

[Djapprentice]

Lol YOUR not getting any DUMMER man!
Hoffman elimination creates terminal alkenes DO TOO steric effects. I have educated thou! Now call me jesus

My kaplan teacher told me that a bulky base like Potassium tert-butoxide produces the Hoffman elimination (less substituted alkene, & the only exception to Zaitstev's rule), are you referring to the bulkiness of the substrate or of the base? The tertiary halide with potassium tert-butoxide!

 

[Manyak222]

They both have a role. Since the base is large, it can only attack where it sees an opening. The whole point to this reaction is to make the leaving group large and use a large base so that the combination of the 2 will only allow either terminal or the least substituted alkenes. Thats what I was taught at least.

My kaplan teacher told me that a bulky base like Potassium tert-butoxide produces the Hoffman elimination (less substituted alkene, & the only exception to Zaitstev's rule), are you referring to the bulkiness of the substrate or of the base? The tertiary halide with potassium tert-butoxide!

 

[Djapprentice]

They both have a role. Since the base is large, it can only attack where it sees an opening. The whole point to this reaction is to make the leaving group large and use a large base so that the combination of the 2 will only allow either terminal or the least substituted alkenes. Thats what I was taught at least.

It makes sense to me, what do you other brainiacs think?