can Someone confirm this for me, at rest, The K+ is inside and Na+ is outside? and vice versa for action potential
Also what is refractory period and what is the proces of it.
At rest there is a greater concentration of K+ inside because at the resting membrane potential the membrane is impermeable to Na+ ions so it cannot come in. Also the Na+/K+ ATP pump maintains this gradient of about -70 mV.
I think K+ leak channels play a role as well but I'm not 100% sure.
The Refractory Period is a period when no Action Potential can be fired. I suggest you read wikipedia for a more detailed explanation...