Hey guys, let me just say off the bat that my #1 criteria is whether I will have a good learning experience at the lab. I am most interested in learning good research methodology and how to think of and approach problems. I've narrowed my search to two professors in cell physiology. They are both outstanding mentors and really understand what I'm looking for. One, who I will refer to as CO, researches the role of a prominent cytoskeletal protein (that she discovered) in pancreatic and breast cancer. The other, JF, researches how collateral arteries develop and their genetic variability. Again, both of them have affirmed to me that they are there to teach me, not to use me as free labor. Here are the facts: CO -Probably slightly more direct contact with the PI than JF. -Lots of cell culturing, some knockout mice. -Investigation of biochemical pathways. -CO is the discoverer of a ubiquitous cytoskeletal protein, which is the focus of her research. -Experiments are shorter than the ones JF does. -Has published fewer articles (she's younger than him) than JF but has three papers of 500+ citations. -Smaller lab than JF. -Allowed her last undergraduate to be listed as an author on a paper. -Lab-wide meetings and potentially one-on-one meetings each week. JF -Experiments depend on rat and mouse surgery, which I would learn how to do. -Molecular techniques also (RT-PCR, western blot, etc). -Investigation of biochemical pathways. -Experiments take longer than with CO because animals must be observed for 1-2 weeks after ligating chosen arteries. -JF has told me that he will be extremely busy for the next year because of grants and training new grad and post-doc students, BUT has also said that he will always make time to meet with me. -Lab-wide meetings, and one-on-one meetings each week. -I feel like tons of undergraduates gravitate towards "hot topics" like cancer, neuro, immunology, etc. and I think this would be more unique research for an undergrad. Again, I have to emphasize that learning is my #1 priority, and both of these PI's have proven that that is their priority also so I'm having trouble making the decision between the two. I'd love to get some input from other pre-meds, med students, MD/Phd students, and really anyone who has been involved with research. Much thanks in advance!