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Does anyone know of any good study that shows without much doubt that taking antihypertensives will prevent strokes? I’m participating in journal club and need this. Surprisingly I havent been able to find one. This is a rather sophisticated audience for journal club so I rather not bring any papers that only quote CDC/AHA expert opinion or that use number games “like relative” risk or having narrow/arbitrary definitions of success (I.e “less days spent in the hospital” or “better motor function after stroke at day 30” or something soft like that). I’m hoping for a nice paper: randomized, placebo controlled, looking for differences in absolute risk, stroke versus no stroke, results that shows a compelling difference. Thanks!!
