Need help with hereditary hemochromatosis

[Little Soldier]

so as i understand it, hfe decreases affinity for transferrin of the transferrin receptor. in HH, the loss of function means increased affinity, then that should cause an elevation in hepcidin released shouldnt it? why is there a decrease?

---

Members don't see this ad.

 

[Amazingmuzmo]

U wut m8?

Aware

 

[Little Soldier]

ur aware but r u a weir?

 

[xffan624]

so as i understand it, hfe decreases affinity for transferrin of the transferrin receptor. in HH, the loss of function means increased affinity, then that should cause an elevation in hepcidin released shouldnt it? why is there a decrease?

I thought you were dropping out...

 

[Little Soldier]

im still enrolled for this semester, i have to take the exams unless i want a withdrawn fail on my transcript

 

[xffan624]

im still enrolled for this semester, i have to take the exams unless i want a withdrawn fail on my transcript

As you're probably unlikely to get back in after dropping out, I'd say that doesn't matter too much.

 

[Little Soldier]

As you're probably unlikely to get back in after dropping out, I'd say that doesn't matter too much.

go **** yourself

 

[xffan624]

go **** yourself

Solid comeback. Real mature.

 

[GangaMaster]

hfe decreases affinity for transferrin of the transferrin receptor.

Does this sentence make sense to anyone else?