So, I am a bit confused as to the difference between the 2 terms. It understand that primary hemochromatosis is iron overload due to a mutation in the HFE gene, but don't really get the difference between secondary hemochromatosis and hemosiderosis. In on part of the text Robbins says that hemosiderosis is the generally benign deposition of hemosiderin in various tissues due to iron overload, BUT in a later part discussing secondary hemochromatosis due to repeated transfusions, it uses hemosiderosis and hemochromatosis interchangebly (RR path also uses secondary hemochromatosis and hemosiderosis interchangebly...). Also, by browsing online, it seems that hemosiderosis refers just to the tissue pathology of having hemosiderin deposits, while hemochromatosis refers in general to iron overload diseases with hemosiderosis as one manifestation of that. Anyone having a clear understanding of the difference between these two terms? Thanks in advance,
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