neupegen and bandemia

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scrambizle

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Can it cause bandemia? Can't find it anywhere.

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It increases proliferation of neutrophils, right? I would imagine anything that does that could potentially cause bandemia.
 
Yes, neupogen can cause a "left-shift" on peripheral smear, along with toxic granulation and dohle bodies in pmns.
 
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Good pimp question, do you know why it is called a "left shift"?
 
Good pimp question, do you know why it is called a "left shift"?

They used to write band forms on the left side of the lab report? or is that total google-derived bs? because i'd be happier with a term defined from FACS or something, but the phrase has obviously been around a lot longer than flow.
 
They used to write band forms on the left side of the lab report? or is that total google-derived bs? because i'd be happier with a term defined from FACS or something, but the phrase has obviously been around a lot longer than flow.

Not quite what I was told.

When they used to use a keypad sort of thing to count cells manually for a differential as they peered into the microscope, the keys to punch in bands were on the left side of the keypad.
 
Not quite what I was told.

When they used to use a keypad sort of thing to count cells manually for a differential as they peered into the microscope, the keys to punch in bands were on the left side of the keypad.

We still use a "keypad-sort-of-thing" to count cells for a manual diff. 😉 And your answer is essentially correct.
This is kind of an older model:
ml9153.jpg


Neupogen can cause problems when looking at a peripheral smear. Generally speaking neupogen causes a "left shift" with many immature granulocytes seen in the peripheral smear including blasts, promyelocytes, myelocytes, and bands. The problem arises when a leukemic patient gets neupogen for neutropenia and has an increase in the number of blasts in the peripheral blood. The difficulty arises when trying to figure out if these are "normal" or leukemic blasts, as what the oncologists will do next will be dramatically different.
 
They used to write band forms on the left side of the lab report? or is that total google-derived bs? because i'd be happier with a term defined from FACS or something, but the phrase has obviously been around a lot longer than flow.

I'm a med tech, and I was taught it was called "left shift" because on many diagrams that show granulocyte maturation the cells mature from left to right. So, any immature cells would represent a "left shift" on the diagram. I don't know about the lab report thing. I think each labs report looks a bit different from other labs.

Not quite what I was told.

When they used to use a keypad sort of thing to count cells manually for a differential as they peered into the microscope, the keys to punch in bands were on the left side of the keypad.

Every cell counter is different, so bands aren't always on a button to the left of segs. I use the ten key pad on a computer at my lab, and bands are right above segs. Bands are 4 and segs are 1.
 
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